Heidelberg bei Nacht
 Deutsche KrebsgesellschaftDeutsche Krebshilfe
17th International AEK Cancer Congress March 20th - 22nd, 2013 · Heidelberg


Wednesday, 20.03.2013

08:00-10:00 Registration
10:00-10:15 Welcome
(Petra Boukamp, Otmar Wiestler, Rainer Engers)
10:30-12:00 Symposium 1: Invasion and metastasis: a different “point of view” - Imaging cancer invasion and therapy
Chair: Rainer Engers, Matthias Dobbelstein
10:30-11:00 Targeting cancer invasion and therapy resistance
(Peter Friedl)
11:00-11:30 Seeing is believing is understanding: real-time microscopy of brain tumor progression and response to therapies
(Frank Winkler)
11:30-11:45 Anti-tumor effects of peptide hormone analogs in pheochromocytoma cell lines and preclinical tumor imaging
(Martin Ullrich)
11:45-12:00 Bevacizumab treatment of HER2 expressing xenograft prevents uptake of fluorescent labeled Trastuzumab: Correlation of in vivo fluorescence imaging with multispectral 3D ultramicroscopy
(Michael Dobosz)
12:00-13:30 Lunch Break
13:30-15:00 Symposium 1 continued: Invasion and metastasis: a different “point of view” - Tracing metastatic cancer
Chair: Nils Cordes, Rainer Engers
13:30-14:00 Circulating tumor cells in cancer patients: Biology and clinical implications
(Klaus Pantel)
14:00-14:30 Metastasis from a radiation oncologist point of view
(Amir Abdollahi)
14:30-14:45 A complex interplay between CD44, the ECM, G-Protein-coupled receptors and Receptor Tyrosine Kinases in tumor progression
(Véronique Orian-Rousseau)
14:45-15:00 Few genes are associated with the capability of pancreatic ductal adenocarcinoma cells to grow in the liver of nude rats
(Hassan Adwan)
15:00-17:30 Poster Session 1 and coffee
17:30-19:00 Symposium 2: Targeting heterogeneous Breast Cancer
Chair: Lisa Wiesmüller, Roland Moll
17:30-18:00 Triple negative breast cancer: Subtypes, molecular targets, and therapeutic apporaches
(Jennifer Pietenpol)
18:00-18:30 Receptor tyrosine kinases in breast cancer: from mechanisms to therapeutic targeting
(Nancy Hynes)
18:30-18:45 EZH2 regulates the heterogenic composition of basal-like breast cancer cell populations
(Ittai Ben-Porath)
18:45-19:00 Development of inhibitors targeting p130Cas as novel therapeutics for breast cancer
(Joerg Kumbrink)
19:30 Welcome Reception „Wine & Cheese“

Thursday, 21.03.2013

08:30-10:00 Symposium 3: Dissecting cancer genomes and epi-genomes
Chair: Martin Lipp, Peter Lichter
08:30-09:00 Dissecting the genome complexity underlying pediatric brain tumors
(Peter Lichter)
09:00-09:30 Probing the cancer methylome
(Stephan Beck)
09:30-09:45 Global DNA methylation signature of HPV-related oropharyngeal squamous cell carcinoma
(Jochen Hess)
09:45-10:00 UVA/UVB-induced epigenetic regulation of tumor suppressor and miRNA gene expression
(Ruediger Greinert)
10:00-10:15 Coffee Break
10:15-11:30 Hunting the elusive oncogene: a stroke of good luck
(Bob Weinberg)
11:30-12:30 Cancer Award
12:30-14:00 Lunch Break
14:00-15:30 Symposium 4: Modelling of oncogenic pathways on the way to clinical pay-off?
Chair: Klaus-Peter Janssen, Reinhold Schäfer
14:00-14:30 Genome analysis, computer modelling and personalized cancer treatment
(Ralf Herwig)
14:30-15:00 Reverse engineering transcriptional networks in cancer cells
(Reinhold Schäfer)
15:00-15:15 DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer
(Markus Morkel)
15:15-15:30 Strong negative feedback from Erk to Raf confers robustness to MAPK signallin
(Christine Sers)
15:30-17:00 Poster Session 2 and coffee
17:00-18:30 Symposium 5: Closing in on the ultimate culprits: the tumor cells and its neighbourhood - Regulatory faults in the tumor cell
Chair: Michael Schwarz, Martin Eilers
17:00-17:30 Targeting Myc and N-Myc for Tumor Therapy
(Martin Eilers)
17:30-18:00 Oncogene-mediated alterations in chromatin conformation
(Mark Rubin)
18:00-18:15 Galectin-8 as a new modulator of K-Ras-induced signaling in carcinoma cell
(Klaudia Giehl)
18:15-18:30 Degradation of macrophage-colony stimulating factor receptor, c-Fms, in epithelial cancer cells is enhanced by induction of autophagy
(Alexandra Koch)
18:30-19:30 AEK Member Assembly
20:00 Social Get-together

Friday, 22.03.2013

08:30-10:00 Symposium 5 continued: - The many faces of the tumor environment
Chair: Jürgen Becker, Holger Kalthoff
08:30-09:00 Cytoprotective signalling pathways in tissue repair and cancer
(Sabine Werner)
09:00-09:30 Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
(Janine T. Erler)
09:30-09:45 Remodelling of the lymphoma-stroma interface within secondary lymphoid organs involves fibroblastic reticular cells and dendritic cells
(Uta Elisabeth Höpken)
09:45-10:00 A genetic mouse model to identify the role of the immune adapter protein MyD88 in colorectal cancer
(Anne Holtorf)
10:00-10:30 Coffee Break
10:30-12:00 Symposium 5 continued
Chair: Klaus Bosslet, Winfried Wels
10:30-11:00 Extracellular trafficking of oncogenes - therapeutic and diagnostic implications
(Janusz Rak)
11:00-11:15 Humanized tumor mice – a new model to investigate and improve cancer therapy
(Anja Kathrin Wege)
11:15-11:30 Towards multi-scale modelling of the patient individual tumor microenvironment
(Niels Grabe)
11:30-12:00 Immunogenic cell death fingerprinting for the detection of adjuvants in cancer therapy
(Oliver Kepp)
12:00-13:30 Lunch Break
13:30-14:30 Key-note Lecture: Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression
Chair: Petra Boukamp
(Mina Bissell)
14:30-14:45 Short Break
14:45-16:00 Symposium 6: Targeted therapy- melanoma a success story?
Chair: Cornelia Mauch, Jens Hoffmann
14:45-15:15 BRAF Inhibitors and beyond
(Meenhard Herlyn)
15:15-15:45 Natural circulating plasmacytoid dendritic cells: Key for antitumor immunity?
(Jolanda de Vries)
15:45-16:00 Preclinical study of combined non-viral gene- and chemotherapy of malignant melanoma
(Wolfgang Walther)
16:00 Poster Prizes and concluding remarks